परिभाषा
Dementia is the progressive loss of memory and various other mental functions, including the ability to learn, reason, and judge. Lewy body disease is associated with the build up of Lewy bodies in regions of the brain. These are abnormal protein deposits inside cells that control certain aspects of memory and motor control.
का कारण बनता है
It is not clear exactly what causes the build up of Lewy bodies in the brain. But the disease is linked to:
- पार्किंसंस रोग
- Multiple system atrophy
- Alzheimer’s disease
- Other disorders
जोखिम कारक
Factors that can increase your chance of developing Lewy body disease include:
- लिंग पुरुष
- Age: 53-83 years
- Family history of Lewy body disease, Parkinson’s disease, or other dementias
लक्षण
Lewy body disease is characterized by:
- Fluctuations in alertness and attention—frequent drowsiness, lethargy, staring into space, disorganized speech, and insomnia
- Recurrent visual hallucinations
- Poor regulation of body temperature and blood pressure
- Obsessive compulsive behaviors
- विस्मृति
- Parkinsonian motor symptoms—rigidity, loss of spontaneous movement
- REM behavior disorder
निदान
The only way to diagnose Lewy body disease is through an autopsy. A doctor can do tests to narrow the cause of dementia. You will be asked about your symptoms and medical history. A physical exam will be done. Other tests may include:
- Memory, language, and other tests
- न्यूरोसाइकोलॉजिकल परीक्षण
- Patient and family interviews
- You may need to have pictures taken of your bodily structures. This can be done with:
- सीटी स्कैन
- एमआरआई स्कैन
- SPECT scan
- You may need to have your bodily fluid tested. This can be done with blood tests.
उपचार
While there is no cure for Lewy body disease, there are treatments that can control the symptoms. Talk with your doctor about the best treatment plan for you. Treatment options include:
दवाएं
These medicines may be used to help with the symptoms:
- Donepezil and rivastigmine—to help with cognition; may worsen motor symptoms
- Memantine—to improve behavioral symptoms
- Levodopa—to help control rigidity and loss of spontaneous movement
- एंटीडिप्रेसन्ट
- Anticonvulsants
If you have Lewy body disease, you may be sensitive to medicines called neuroleptics. You may have adverse events with these medicines.
अन्य उपचार
You may benefit from:
- शारीरिक चिकित्सा
- मालिश
- व्यायाम
- Music
- aromatherapy
रोकथाम
इस स्थिति को रोकने का कोई ज्ञात तरीका नहीं है।