Definition
Dandy-Walker syndrome is a brain deformity that develops before birth. The deformity occurs in an area in the back of the brain. This area controls movement and cognitive learning. This syndrome can also affect fluid-filled chambers of the brain called ventricles. The ventricles may have an abnormal build-up of fluid.
Causes
It is not clear what causes Dandy-Walker syndrome. There may be a genetic factor.
Risk Factors
Dandy-Walker syndrome may be inherited. If a parent has Dandy-Walker syndrome, the child has a higher risk of the condition. There are no other known risk factors.
Symptoms
Symptoms of Dandy-Walker syndrome often occur in infancy. Some may not appear until childhood. Most are found within the first year of life. Symptoms may include:
- Impaired development of normal speech and language
- Slow motor development
- Irritability
- Vomiting
- Unsteadiness
- Lack of muscle coordination
- Jerky eye movements
- Increased head size
- Bulging of the back of the skull
- Abnormal breathing
- Trouble with vision or hearing
- Seizures
Children with this syndrome may also have other birth deformities of the brain, heart, face, or limbs.
Diagnosis
Your doctor will ask about your child’s symptoms and medical history. A physical exam will be done.
Your doctor may also order test to take details pictures of the brain. This will help show changes to the ventricles. Pictures may be made with:
- CT scan
- MRI scan
- Ultrasound
Treatment
Dandy-Walker syndrome cannot be treated. Instead, treatment will focus on managing symptoms.
The build-up of fluid in the ventricles may need treatment. Extra fluid can cause increased pressure and swelling in the brain. Fluid may be drained by:
- Shunt—a tube is placed in the brain to allow the extra fluid to drain out of the brain.
- Ventriculostomy—a tube from one ventricle to another. It allows extra fluid to drain out of the affected ventricle.
Talk with your doctor about the best treatment plan.
Prevention
There is no known way to prevent this syndrome.
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