সংজ্ঞা
Henoch-Schonlein purpura (HSP) is swelling of the blood vessels in the skin and other body organs. When it involves the skin it causes a telltale rash. The rash looks like bruising or small dots in the skin, referred to as “purpura.
People of all ages may develop HSP, but it is most common in children.
কারণসমূহ
HSP is caused by an abnormal reaction of the immune system. Normally the immune system marks and attacks foreign items like viruses and bacteria. However, with HSP, the immune system attack the blood vessels. It is not clear why the immune system attacks the body.
The change in the immune system It may be triggered by:
- Bacterial or viral infections
- কিছু ওষুধ
- Recent exposure to certain vaccines
- Infection by insect bites
HSP occurs most often after a respiratory infection. HSP is not contagious.
ঝুঁকির কারণ
HSP is most common in children aged 2 to 11 years old but can occur at any age. Factors that increase your risk of HSP include:
- Recent upper respiratory illness, such as a cold
- Recent exposure to vaccines, chemicals, cold weather, or insect bites
লক্ষণ
Symptoms may last for 4 to 6 weeks and may include:
- Skin rash:
- Reddish-purple spots that are not itchy
- Often appears on the buttocks or legs, may appear on the elbows
- Pain in the joints, especially knees and ankles
- পেটে ব্যথা
- Blood or protein in the urine caused by kidney inflammation
- Swelling of the ankles
- Swelling of the scrotum in males
- জ্বর
- মলে রক্ত
- বমি
রোগ নির্ণয়
আপনার ডাক্তার আপনার লক্ষণ এবং চিকিৎসা ইতিহাস সম্পর্কে জিজ্ঞাসা করবে। একটি শারীরিক পরীক্ষা সম্পন্ন করা হবে। পরীক্ষা অন্তর্ভুক্ত হতে পারে:
- রক্ত পরীক্ষা
- ইউরিনালাইসিস
- মলের নমুনা
- Skin biopsy from an area of the rash
চিকিৎসা
HSP usually gets better on its own. Your doctor may prescribe medications if symptoms or complications are causing problems. Medications may include:
- Nonsteroidal anti-inflammatory drugs (NSAIDs)—to lessen joint pain and arthritis
- Steroid medication—for significant abdominal pain, joint pain, or kidney disease
- Antibiotics—to treat bacterial infection
- Cyclophosphamide ( Cytoxan )—to suppress the immune system when you have symptoms of severe kidney disease
প্রতিরোধ
There are no guidelines for the prevention of HSP. Relapse occurs in about 50% of cases.
It is important to make sure that you have long-term, follow-up visits with your doctor to be sure that kidney disease doesn’t develop.