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أسباب

Gilbert’s syndrome is usually caused by an inherited genetic abnormality. Symptoms occur when there is an interference with the liver enzyme that is important in the elimination of bilirubin. This causes the levels of bilirubin to increase in the blood, which may produce symptoms such as jaundice.

عوامل الخطر

A risk factor is something that increases your chance of getting a disease or condition. The risk factors for Gilbert’s syndrome are:

• Family members with Gilbert’s syndrome (autosomal dominant trait)—People who have Gilbert’s syndrome have a 50% chance of passing it on to each of their children.
• الجنس : ذكر

الأعراض

Often, there are no symptoms of Gilbert’s syndrome. However, people who do have symptoms may experience:

• Jaundice (yellowing) of the whites of the eyes
• Jaundice of the skin
• ألم في البطن
• فقدان الشهية
• Fatigue and weakness
• Darkening of the urine

التشخيص

Your doctor will ask about your symptoms and medical history and perform a physical exam . Tests may include:

• تعداد الدم الكامل (CBC)
• اختبارات وظائف الكبد

Blood tests are also done to rule out more serious liver diseases, such as hepatitis. Sometimes, a liver biopsy may also need to be done to rule out other liver diseases.

العلاج

No treatment is necessary for Gilbert’s syndrome. Usually, symptoms will disappear on their own.

الوقاية

There is no way to prevent Gilbert’s syndrome. However, you may prevent symptoms by avoiding the following:

• Skipping meals or fasting
• Dehydration (too little fluid in the body)
• Vigorous exercise
• Repeated bouts of vomiting
• Stress or trauma